What is the MMC?
The MMC is a wave of muscle contractions that moves through the stomach and small intestine roughly every 90 to 120 minutes when you are not eating. It sweeps leftover food, bacteria and debris toward the large intestine. It only works in a fasting state — eating interrupts it.
Why a weak MMC leads to SIBO
When the cleaning waves are weak or too infrequent, bacteria linger and multiply in the small intestine. That is why SIBO relapse is so common: the overgrowth can be reduced, but if the underlying motility problem remains, it tends to return.
What can disrupt the MMC
- Food poisoning or gastroenteritis (post-infectious IBS)
- Hypothyroidism
- Diabetes and blood sugar dysregulation
- Chronic stress and poor sleep
- Certain medications, such as opioids
- Constant snacking
Supporting your MMC
- Leave four to five hours between meals, without snacks
- Allow a 12-hour overnight fast
- Manage stress and support the vagus nerve (breathing, calm eating)
- Address underlying causes together with your physician
- Prokinetic support may be discussed during the recovery phase
This article is for general information and does not replace medical advice. Medical decisions, medication and prescriptions always remain with your physician.
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